Manuscripts

1.  Mancha, S. *, Regnery, C.M.*, Dahlke, J.R.*, Miller, K., Blake, D.J. 2013. Antiviral Activity of (+)-Sattabacin Against Varicella Zoster. Bioorganic and Medical Chemistry Letters. 23: 562-564 * denotes undergraduate student

2. Starrett, W.*, Blake, D.J. 2011. Sulforaphane inhibits de novo synthesis of IL-8 and MCP-1 in human epithelial cells generated by cigarette smoke extract. Journal of Immunotoxicology. 8: 150-158. * denotes undergraduate student

3. Guo, H., Li, M., Chen, P., Blake, D.J., Kong, X., Hao, X., Niu, R., Zhang, N. 2011. 4-Methyl-3-nitro-benzoic acid, a migration inhibitor, prevents breast cancer metastasis in SCID mice. Cancer Letters. 305:69-75.

4. Blake, D.J., Singh, A., Kombairaju, P., Malhotra, D., Mariani, T.J., Tuder, R.M., Gabrielson, E., Biswal, S. 2009. Deletion of Keap1 in the lung attenuates acute cigarette smoke-induced oxidative stress and inflammation. American Journal of Respiratory and Cell and Molecular Biology. 42: 524-536.

5. Sussan, T.E. †, Rangasamy, T. †, Blake D.J. †, Malhotra, D., El-Haddad, H., Bedja, D., Yates, M.S., Yamamoto, M., Liby, K.T., Sporn, M.B., Gabrielson, K.L., Champion, H.C., Tuder, R.M., Kensler, T.W., Biswal, S. 2009. Targeting the Nrf2 Pathway with the Synthtic Triterpenoid, CDDO-Imidazole, Attenuates Cigarette Smoke-Induced Emphysema and Cardiac Dysfunction in Mice. Proceedings of the National Academy of Sciences. 106: 250-255. † denotes equal contributing author

6. Harvey, C., Thimmulappa, R.K., Singh, A., Blake, D.J., Ling, G., Wakabayashi, M., Fujii, J., Myers, A., Biswal, S. 2008. Nrf2 maintains Glutathione Homeostasis by Regulating Glutathione Reductase and Protects from Oxidative Stress. Free Radical Biology & Medicine. 46: 443-453.

7. Webber, J., Blake, D.J., Pfau, J.C., Ward, T. 2008. Separation and Characterization of Respirable Amphibole Fibers from Libby, Montana. Inhalation Toxicology. 20: 733-740.

8. Blake, D.J., Wetzel, S.A., Pfau, J.C. 2008. Autoantibodies from mice exposed to Libby amphibole asbestos bind SSA/Ro52-enriched apoptotic blebs of murine macrophages. Toxicology. 246: 172-179.

9. Pfau, J.C., Sentissi, J.J., Blake, D.J., Li, S., Calderon-Garceduenas, L., Brown, J.M. 2008. Asbestos-induced Autoimmunity in C57Bl/6 mice. Journal of Immunotoxicology. 2: 129-137.

10. Blake, D.J., Bolin, C.M., Cox, D.P., Cardozo-Pelaez, F., Pfau, J.C. 2007. Internalization of Libby amphibole asbestos and induction of oxidative stress in murine macrophages. Toxicological Sciences. 99: 277-288.

11. Blake, D.J., Graham, J., Poss, M. 2006. Quantification of Feline Immunodeficiency Virus (FIVpco) in peripheral blood mononuclear cells, lymph nodes and plasma of naturally infected cougars. Journal of General Virology. 87: 967-975.

12. Yan, Q., Perdue, N., Blake, D., Sage, H.E. 2005. Absence of SPARC in murine lens epithelium leads to increased deposition of laminin-1 in lens capsule. Investigative Ophthalmology and Visual Science. 46: 4652-60.

13. Yan, Q., Blake, D., Clark, J.I., Sage, E.H. 2003. Expression of the Matricellular Protein SPARC in Murine Lens: SPARC Is Necessary for the Structural Integrity of the Capsular Basement Membrane. Journal of Histochemistry and Cytochemistry. 51: 503-511.

14. Motamed, K., Blake, D.J., Angello, J.G., Allen, B.L., Rapreager, A.C., Hauschka, S.D., Sage, E.H. 2003. Fibroblast Growth Factor Receptor-1 Mediates the Inhibition of Endothelial Cell Proliferation and the Promotion of Skeletal Myoblast Differentiation by SPARC: A Role for Protein Kinase A. Journal of Cellular Biochemistry. 90: 408-423.

15. Franki, A., Motamed, K., McClure, T.D., Kaya, M., Murri, C., Blake, D.J., Carbon, J.G., Sage, H.E. 2003. SPARC Regulates Cell Cycle Progression in Mesangial Cells via its Inhibition of IGF-dependant Signaling. Journal of Cellular Biochemistry. 88: 802-11.

16. Maris, J.M., Guo, C., Blake D., White, P.S., Hogarty, M.D., Thompson, P.M., Rajalingam, V., Gerbing, R., Stram, D.O., Matthay, K.K., Seeger, R.C., Brodeur, G.M. 2001. Comprehensive analysis of chromosome 1p deletions in neuroblastoma. Medical and Pediatric Oncology. 36: 32-36.

Book Chapters

Pfau, J.C., Blake, D.J., Fritzler, M.J. 2008. Autoantibody Profiles of an Asbestos-Exposed Population. "Autoimmunity: Roles, Regulations and Disorders" Nova Science Publishers, Inc. Hauppauge NY. In Press.

Abstracts

1. Mancha, S. *, Miller, K., Blake, D.J. 2012. Does Sattabacin inhibit viral replication of the varicella-zoster virus in human fibroblast cells? Society for Advancement of Chicanos and Native Americans in Science, Seattle, WA. * denotes undergraduate student

2. Charley, P.*, Blake, D.J., 2012. Sulforaphane restores histone deacetylase activity in human epithelial cells exposed to cigarette smoke resulting in decreased cytokine production. Society of Toxicology Meeting, San Francisco, CA. * denotes undergraduate student

3. Blake, D.J. 2011. Sulforaphane inhibits de novo synthesis of IL-8 and MCP-1 in human epithelial cells generated by cigarette smoke extract. American Thoracic Society, Denver, CO.

4. Blake, D.J., Biswal S. 2010. Inhibition of cigarette smoke-induced chemokine production by the Nrf2 activator sulforaphane. Society of Toxicology Meeting, Salt Lake City, UT.

5. Kong, X., Thimmulappa, R., Kombairaju, P., Blake, D.J., Craciun, F., Remick, D., Biswal, S. 2009. Nrf2 is essential in innate immune cells for survival in sepsis. Shock Conference. San Antonio, Texas.

6. Blake, D.J., Singh, A., Kombairaju, P., Biswal, S. 2009. Deletion of Keap1 in lung attenuates acute cigarette smoke-induced oxidative stress and inflammation. American Thoracic Society Meeting, San Diego, CA.

7. Sussan, T.E., Rangasamy, T., Blake, D.J., Malhotra, D., El-Haddad, H., Bedja, D., Yates, M.S., Kombairaju, P., Yamamoto, M., Liby, K.T., Sporn, M.B., Gabrielson, K.L., Champion, H.C., Tuder, R.M., Kensler, T.W., Biswal, S. 2009. Targeting Nrf2 with the Triterpenoid CDDO-Imidazolide Attenuates Cigarette Smoke-Induced Emphysema and Cardiac Dysfunction in Mice. American Thoracic Society Meeting, San Diego, CA.

8. Rangasamy, T., Sussan, T.E., Blake, D., Tuder, R.M., Wilson, C., B., Biswal, S. 2008. Inhibition of NF-KB in distal airway epithelial cells causes spontaneous emphysema in mice. American Thoracic Society Meeting, Toronto, Canada.

9. Blake, D.J., Li, S., Pfau, J.C. 2007. Libby amphibole asbestos is internalized and induces oxidative stress in macrophages; a possible mechanism for asbestos-induced autoantibody production. American Thoracic Society Meeting, San Francisco, CA

10. Blake, D.J., Pfau J.C. 2006. Libby amphibole asbestos induces oxidative stress in murine macrophages, Pacific Northwest Society of Toxicologists Meeting, Missoula, MT.

11. Blake, D.J., Li, S., Fritzler, M.J., Pfau J.C. 2006. Serological polyreactivity in serum samples from an asbestos-exposed community: Libby MT. American Association of Immunologists Meeting, Boston, MA.

12. Blake, D.J., Pfau J.C. 2006. Defining a mechanism for asbestos-induced autoantibody production. College of Arts & Sciences Graduate Student and Faculty Research Conference. University of Montana, Missoula MT.

13. Blake, D.J., Graham, J., Poss, M. 2005. Quantification of Feline Immunodeficiency Virus (FIVpco) in peripheral blood mononuclear cells, lymph nodes and plasma of naturally infected cougars. Annual Meeting of the American Society of Virology. The Pennsylvania State University, State College, PA.

14. Blake, D.¸ Poss, M. 2004. Proviral Quantification of Feline Immunodeficiency Virus (FIVpco) in naturally infected cougars. College of Arts & Sciences Graduate Student and Faculty Research Conference. University of Montana, Missoula MT.

15. Yan, Q., Blake, D., Wight, T., Clark, J.I., Sage, E.H. 2002. Compromised permeability of the lens capsule contributes to cataract formation in SPARC-null mice. Association for Research in Vision and Ophthalmology Meeting, Fort Lauderdale, FL.

16. Sage, E.H., Yan, Q., Blake, D., Clark, J.I. 2002. Expression of SPARC in murine lens. Association for Research in Vision and Ophthalmology Meeting, Fort Lauderdale, FL.

17. Motamed, K., Allen, B., Blake, D.J., Zhu, W.H., Claesson-Welsh, L., Nicosia, R., Rapraeger, A.C., Sage, E.H. 2002. SPARC inhibits FGF-2 activity in vitro and ex vivo. Joint Keystone Symposia on Angiogenesis in Cancer and Other Diseases: From Genes to Function to Therapy and Biological Response to Extracellular Matrix. Banff, Alberta, Canada.