Selected Publications

† denotes underrepresented minority student, * denotes undergraduate student, Δ denotes equal contributing author

Manuscripts (most recent 10 of 17)

Lehmer, E.M., Lavengood, K. *, Miller, M. *, Rodgers, J. *, Blake, D.J., Fenster, S.D. 2016. Evaluating the Impacts of Co-Infection on Immune System Function of Wildlike Using Hantavirus and Bartonella as Model Disease Systems. Physiological and Biochemical Zoology. In Review.

Blake, D.J., Reese, C.M.*, Garcia, M.†*, Dahlmann, E.A.*, Dean, A.M.*, 2015. Soluble extracellular Klotho decreases sensitivity to cigarette smoke induced cell death. Toxicology In Vitro.29:1647-1652.

Mancha, S.†*, Regnery, C.M.*, Dahlke, J.R.*, Miller, K., Blake, D.J. 2013. Antiviral Activity of (+)-Sattabacin Against Varicella Zoster. Bioorganic and Medical Chemistry Letters. 23: 562-564

Starrett, W.*, Blake, D.J. 2011. Sulforaphane inhibits de novo synthesis of IL-8 and MCP-1 in human epithelial cells generated by cigarette smoke extract. Journal of Immunotoxicology. 8: 150-158.

Guo, H., Li, M., Chen, P., Blake, D.J., Kong, X., Hao, X., Niu, R., Zhang, N. 2011. 4-Methyl-3-nitro-benzoic acid, a migration inhibitor, prevents breast cancer metastasis in SCID mice. Cancer Letters. 305:69-75.

Blake, D.J., Singh, A., Kombairaju, P., Malhotra, D., Mariani, T.J., Tuder, R.M., Gabrielson, E., Biswal, S. 2009. Deletion of Keap1 in the lung attenuates acute cigarette smoke-induced oxidative stress and inflammation. American Journal of Respiratory and Cell and Molecular Biology. 42: 524-536.

Sussan, T.E.Δ, Rangasamy, T.Δ, Blake D.J.Δ, Malhotra, D., El-Haddad, H., Bedja, D., Yates, M.S., Yamamoto, M., Liby, K.T., Sporn, M.B., Gabrielson, K.L., Champion, H.C., Tuder, R.M., Kensler, T.W., Biswal, S. 2009. Targeting the Nrf2 Pathway with the Synthtic Triterpenoid, CDDO-Imidazole, Attenuates Cigarette Smoke-Induced Emphysema and Cardiac Dysfunction in Mice. Proceedings of the National Academy of Sciences. 106: 250-255.

Harvey, C., Thimmulappa, R.K., Singh, A., Blake, D.J., Ling, G., Wakabayashi, M., Fujii, J., Myers, A., Biswal, S. 2008. Nrf2 maintains Glutathione Homeostasis by Regulating Glutathione Reductase and Protects from Oxidative Stress. Free Radical Biology & Medicine. 46: 443-453.

Webber, J., Blake, D.J., Pfau, J.C., Ward, T. 2008. Separation and Characterization of Respirable Amphibole Fibers from Libby, Montana. Inhalation Toxicology. 20: 733-740.

Blake, D.J., Wetzel, S.A., Pfau, J.C. 2008. Autoantibodies from mice exposed to Libby amphibole asbestos bind SSA/Ro52-enriched apoptotic blebs of murine macrophages. Toxicology. 246: 172-179.

Pfau, J.C., Sentissi, J.J., Blake, D.J., Li, S., Calderon-Garceduenas, L., Brown, J.M. 2008. Asbestos-induced Autoimmunity in C57Bl/6 mice. Journal of Immunotoxicology. 2: 129-137.

Book Chapters

Pfau, J.C., Blake, D.J., Fritzler, M.J. 2008. Autoantibody Profiles of an Asbestos-Exposed Population. "Autoimmunity: Roles, Regulations and Disorders" Nova Science Publishers, Inc. Hauppauge NY. In Press.

Abstracts (most recent 10 of 20)

Njenga, M. †*, Lone, T*. Blake, D.J., 2016. Identification of the Cleaved Klotho Protein That Protects Against Oxidative Cigarette Smoke Induced Cell Death. Society of Toxicology Meeting, Phoenix, AZ.

Garcia, M. †*, Blake, D.J. 2014. Klotho overexpression in human lung epithelial cells decrease sensitivity to cigarette smoke induced cell death. Society for Advancement of Chicanos and Native Americans in Science, Los Angeles, CA.

Blake, D.J., 2013. Klotho overexpression in human lung epithelial cells decrease sensitivity to cigarette smoke induced cell death. Society of Toxicology Meeting, Phoenix, AZ.

Mancha, S. †*, Miller, K., Blake, D.J. 2012. Does Sattabacin inhibit viral replication of the varicella-zoster virus in human fibroblast cells? Society for Advancement of Chicanos and Native Americans in Science, Seattle, WA.

Charley, P. †*, Blake, D.J., 2012. Sulforaphane restores histone deacetylase activity in human epithelial cells exposed to cigarette smoke resulting in decreased cytokine production. Society of Toxicology Meeting, San Francisco, CA.

Blake, D.J. 2011. Sulforaphane inhibits de novo synthesis of IL-8 and MCP-1 in human epithelial cells generated by cigarette smoke extract. American Thoracic Society, Denver, CO.

Blake, D.J., Biswal S. 2010. Inhibition of cigarette smoke-induced chemokine production by the Nrf2 activator sulforaphane. Society of Toxicology Meeting, Salt Lake City, UT.

Kong, X., Thimmulappa, R., Kombairaju, P., Blake, D.J., Craciun, F., Remick, D., Biswal, S. 2009. Nrf2 is essential in innate immune cells for survival in sepsis. Shock Conference. San Antonio, Texas.

Blake, D.J., Singh, A., Kombairaju, P., Biswal, S. 2009. Deletion of Keap1 in lung attenuates acute cigarette smoke-induced oxidative stress and inflammation. American Thoracic Society Meeting, San Diego, CA.

Sussan, T.E., Rangasamy, T., Blake, D.J., Malhotra, D., El-Haddad, H., Bedja, D., Yates, M.S., Kombairaju, P., Yamamoto, M., Liby, K.T., Sporn, M.B., Gabrielson, K.L., Champion, H.C., Tuder, R.M., Kensler, T.W., Biswal, S. 2009. Targeting Nrf2 with the Triterpenoid CDDO-Imidazolide Attenuates Cigarette Smoke-Induced Emphysema and Cardiac Dysfunction in Mice. American Thoracic Society Meeting, San Diego, CA.