Faculty mentors are available in all of the scientific disciplines at Fort Lewis College. Contact Dr. Les Sommerville, Program Director, for a listing.
Dr. David Blake, Professor of Biology
B.A., 1999, University of Pennsylvania
M.S., 2005, University of Montana
Ph.D., 2007, University of Montana
Post Doctoral Fellow, 2007-2009, Johns Hopkins University, Maryland
Dr. Blake started working with Serena Mancha fist as a Pre-MARC student and then as a MARC awardee. Their research is on Herpes simplex virus type 3 (HSV3), commonly known as the Varicella zoster virus (VZV), which is a DNA virus within the Herpesviridae family. Infection with VZV in children results in chickenpox (varicella), and reactivation of the virus in the elderly or in immunocompromised adults leads to shingles (zoster). Due to the aging population in the United States, new compounds against VZV infection must be developed and tested for anti-viral efficacy. They hypothesize that sattabacin, a natural related compounds product recently synthesized by Dr. Kenny Miller in the Chemistry Department at FLC and other structurally related compounds will have anti-viral activity against VZV infection in human fibroblast cells.
Dr. Melissa Knight-Maloney, Professor of Exercise Science
Phone: (970) 247-7632
B.A., 1989, Fort Lewis College
M.S., 1993, University of New Mexico
Ph.D., 1999, University of New Mexico
Dr. Knight-Maloney is working with MARC scholar Jacob Montoya, who is an exercise science major. Their research is examining the effects of age and activity level on heart rate variability (HRV). HRV has previously been defined in the literature as the variations in cardiac rhythm as a response to Autonomic Nervous System (ANS). HRV can be measured using an ECG (Electrocardiogram) and calculated by determining the R to R interval. Research subject’s HRV will be measured using a 3 lead ECG and grouped according to age and hours spent exercising. Jacob anticipates that older, less active individuals will a have decreased HRV.
Dr. Sue Kraus, Professor of Psychology
B.S., 1988, Penn State University
M.A., 1991, University of Colorado
Ph.D., 1993, University of Colorado
Dr. Krause serves on the MARC Steering Committee in addition to her role as a MARC mentor. Dr. Kraus has developed a new line of research centering on historic trauma in Native American populations. This is a new area of research for Dr. Kraus, and all of the work has been done as a team with Noel Altaha, MARC Awardee (2011-2013). During the academic year of 2011-2012, they conducted an in-depth look at the existing literature and design and implemented a preliminary study of historic trauma for current Native American students at FLC. The effects of historical trauma in Native Americans have been researched previously, but only within older generations. Previous research found clear evidence that past generations of Native Americans suffer significant effects from their history of trauma stemming from the loss of land and culture. This study examined the effects of historical trauma in current Native American college students. Seventy Native American students from 28 tribes (56% identified Navajo as their primary tribal affiliation) were surveyed on psychological measures including depression, anxiety, resilience, coping abilities, compassion towards oneself and towards others, and historical trauma. Noel and Dr. Kraus found that the current generation of Native American college students continues to experience levels of historical trauma similar to older generations. Native American students who experience historical loss have higher levels of depression, anxiety, negative feelings towards oneself and lower levels of resilience. They found that historical trauma was not correlated with blood quantum, gender, SES, or drug and alcohol use. These findings suggest a need for more research on the effects and potential treatment to increase resilience and reduce the impact of historical trauma.
Dr. Erin Lehmer, Professor of Biology
Phone: (970) 247-7024
B.S., 1997, Fort Lewis College, Colorado
M.S., 2000, Colorado State University
Ph.D., 2004, Colorado State University
Dr. Lehmer serves on the MARC Steering Committee and has mentored a MARC student. The objective of Dr. Lehmer’s research is to determine the role that immunocompetence plays in the susceptibility of wild mammals to simultaneous infection with multiple pathogens. Her research group is working on determining 1) the extent to which maintaining a chronic infection with Sin Nombre virus (SNV) affects the immune system function of wild deer mice and 2) the extent to which immunocompetence influences the susceptibility of deer mice to co-infection with the bacterial pathogen, Bartonella. They are conducting a field and lab-based study in which they compare the innate, inflammatory and virus-specific immunity of SNV-infected deer mice to their uninfected counterparts. Likewise, the immunity of deer mice who are co-infected with both Bartonella and SNV are being compared to individuals who are either uninfected or infected with only 1 of these pathogens. Results of this research will provide much needed information regarding the regulation of both bacterial and viral disease in wild animals, ultimately improving the ability to predict patterns of zoonotic disease transmission among animals and from animals to humans.
Dr. Kenny Miller, Professor of Chemistry
B.S., 2002, University of Georgia, Athens
Ph.D., 2007, University of Texas, Austin
Postdoctoral Fellow, 2007-2009, Colorado State University, Fort Collins
Dr. Miller currently serves on the MARC Steering Committee. He is available to mentor both Pre-MARC and MARC students. His research interests include synthetic organic chemistry with an emphasis on the laboratory preparation of biologically active natural products (drugs) with potential to treat viral infections and cancer. Most recently, Dr. Miller’s research group synthesized the antiviral compounds sattabacin and sattazolin. Serena Mancha, MARC Scholar, and Dr. David Blake studied the antiviral activity of sattabacin against Varcella Zoster Virus (VZV) infection in human fibroblast cells.
Dr. Aimee Morris, Professor of Chemistry
B.S., 2004, Western Washington University
Ph.D., 2009, Colorado State University
Neuro-postdoctoral fellow, 2009-2010, Brandeis University
Adjunct Faculty, 2010-2011, Massachusetts College of Pharmacy and Health Sciences
Faculty Associate, 2011-2012, Massachusetts College of Pharmacy and Health Sciences
Dr. Morris is currently working with a Pre-MARC student to develop a new pathway for the synthesis of the cobalt(III) coordination complex, [CoIII(pyridine)4Cl2]Cl . Historically, chlorine gas has been used during the synthesis process both to oxidize the Co(II) starting material and to add the chlorine counterion. Chlorine gas is highly toxic and corrosive. Dr. Morris’s research group proposes using a hydrogen peroxide solution to synthesize [CoIII(pyridine)4Cl2]Cl. The synthesis of the counterpart cobalt II coordination complex, trans-[CoII(pyridine)4Cl2], using an established technique from the literature, will also be undertaken. Once synthesis of both complexes are complete, they plan to work on obtaining physical measurements. In the future, Dr. Morris’s group plans to use both complexes as teaching tools in inorganic lab courses, as they demonstrate synthetic techniques, varying oxidation states of metals, symmetry, ligand field theory, and diamagnetic vs. paramagnetic coordination complexes.
Dr. Kathryn Mouzakis, Professor of Chemistry
B.S., 2007, Harvey Mudd College
Ph.D., 2013, University of Wisconsin - Madison
Post-Doc., 2013 University of Wisconsin – Madison
Dr. Mouzakis is currently working with a senior MARC student. Her personal research interests focus on understanding the relationship between the structure and function of cis-acting viral RNAs. Student laboratory projects have covered a variety of biochemical topics: from using NMR to determine RNA secondary structures to elucidating the mechanism of -1 programmed ribosomal frameshifting (PRF). Currently, her lab is utilizing mutagenesis, chemical probing, and in vitro translation assays to determine what RNA structures are required for efficient -1 PRF in human t-cell lymphotropic virus.
Dr. Les Sommerville, Professor and Chair of Chemistry
B.S., 1980, Fort Lewis College, Colorado
Ph.D., 1985, University of Minnesota
NIH Postdoctoral Fellow, 1986-1988, University of Arizona
Faculty, 1988-1989, Bates College, Maine
Faculty, 1989-1991, St. Lawrence University, New York
Dr. Sommerville is the Director of the MARC U*STAR Program at Fort Lewis College. He has been mentor to two MARC trainees since 2010 and a mentor to three pre-MARC students since 2013. The research projects in Dr. Sommerville’s lab are genome-directed studies done to understand glucose metabolism and enzymology in an organism, Acidobacterium capsulatum, which is prevalent in soil and aquatic environments around the globe. Students in Dr. Sommerville’s lab are currently working on NMR-based metabolic profiling with glucose as a sole carbon source, cloning key enzymes involved in glucose metabolism and developing cell lysis techniques to retrieve active enzymes from cell lysates. The long-term goal is to understand how these organisms acquire energy from the environment around them, regulate energy consumption and control glucose utilization for energy and biomass production.